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Home > Products >  ABT-888

ABT-888 CAS NO.912444-00-9

  • Min.Order: 1 Metric Ton
  • Payment Terms: T/T,
  • Product Details

Keywords

  • ABT-888
  • Veliparib
  • 912444-00-9

Quick Details

  • ProName: ABT-888
  • CasNo: 912444-00-9
  • Appearance: white powder
  • DeliveryTime: within 3 days after payment
  • PackAge: 25kg/drum
  • Port: Shanghai, Shenzhen, Guangzhou, Hongkon...
  • ProductionCapacity: 1 Metric Ton/Day
  • Purity: >98%
  • Storage: Kept in a cool, dry and ventilated pla...
  • LimitNum: 1 Metric Ton
  • Moisture Content: <0.5%
  • Impurity: <0.2%

Superiority

 

Product Name:ABT-888(Veliparib)
Synonyms:MX-1,ABT888 
Cas No.:912444-00-9 
Molecular Formula:C13H16N4O
Molecular Weight:244.29 
Purity:98% 
Apperarnce:white solid 

 

Details

 

Product Name:ABT-888(Veliparib)
Synonyms:MX-1,ABT888 
Cas No.:912444-00-9 
Molecular Formula:C13H16N4O
Molecular Weight:244.29 
Purity:98% 
Apperarnce:white solid 

Potent inhibitor of PARP-1 and PARP-2 (potency <5nM in vitro). Does not inhibit other NAD-binding enzymes.Has minimal CYP450 inhibition and induction.Shows broad spectrum of chemo- and radiopotentiation. Enantiomeric purity >97% suitable for in vivo studies. Does not show inherent cytotoxicity and shows no single agent activity in tumor models. Has excellent bioavailability and good blood-brain permeation. Increases tumor growth delay resulting from radiation and DNA-damaging agents.

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