- Product Details
Keywords
- ABT-888
- Veliparib
- 912444-00-9
Quick Details
- ProName: ABT-888
- CasNo: 912444-00-9
- Appearance: white powder
- DeliveryTime: within 3 days after payment
- PackAge: 25kg/drum
- Port: Shanghai, Shenzhen, Guangzhou, Hongkon...
- ProductionCapacity: 1 Metric Ton/Day
- Purity: >98%
- Storage: Kept in a cool, dry and ventilated pla...
- LimitNum: 1 Metric Ton
- Moisture Content: <0.5%
- Impurity: <0.2%
Superiority
Product Name:ABT-888(Veliparib) |
Synonyms:MX-1,ABT888 |
Cas No.:912444-00-9 |
Molecular Formula:C13H16N4O |
Molecular Weight:244.29 |
Purity:98% |
Apperarnce:white solid |
Details
Product Name:ABT-888(Veliparib) |
Synonyms:MX-1,ABT888 |
Cas No.:912444-00-9 |
Molecular Formula:C13H16N4O |
Molecular Weight:244.29 |
Purity:98% |
Apperarnce:white solid |
Potent inhibitor of PARP-1 and PARP-2 (potency <5nM in vitro). Does not inhibit other NAD-binding enzymes.Has minimal CYP450 inhibition and induction.Shows broad spectrum of chemo- and radiopotentiation. Enantiomeric purity >97% suitable for in vivo studies. Does not show inherent cytotoxicity and shows no single agent activity in tumor models. Has excellent bioavailability and good blood-brain permeation. Increases tumor growth delay resulting from radiation and DNA-damaging agents.