China (Mainland)
AG-014699 CAS NO.459868-92-9
- Min.Order: 1 Metric Ton
- Payment Terms: T/T,
- Product Details
Keywords
- AG-014699
- Rucaparib
- 459868-92-9
Quick Details
- ProName: AG-014699
- CasNo: 459868-92-9
- Appearance: white powder
- DeliveryTime: within 3 days after payment
- PackAge: 25kg/drum
- Port: Shanghai, Shenzhen, Guangzhou, Hongkon...
- ProductionCapacity: 1 Metric Ton/Day
- Purity: >99%
- Storage: Kept in a cool, dry and ventilated pla...
- LimitNum: 1 Metric Ton
- Moisture Content: <0.5%
- Impurity: <0.2%
Superiority
| Product Name:AG-014699 |
| Synonyms:Rucaparib,PF-01367338，AG-14447,AG014699 |
| Cas No.:459868-92-9 |
| Apperarnce:off-white powder |
|
M.Wt: 421.36 Formula: C19H21FN3O5P Solubility: Soluble in water Purity: >99% Storage: -20℃ 2 years |
Details
AG014699, the phosphate salt of AG14447, which has improved aqueous solubility, has been selected for clinical trial.AG014699 is a tricyclic indole poly(ADP-Ribose) polymerase (PARP) inhibitor with potential antineoplastic activity. PARP-1 inhibitor AG014699 blocks base excision repair mediated by PARP 1 on single strand breaks and may be particularly efficacious in inducing apoptosis in breast cancer associated gene-1 and -2 (BRCA1/2) deficient tumor cells.